Acetyl L-Carnitine

…to the rescue…

Here’s why CFS/ME sufferers need to keep this one in their daily supplement routine:

“Carnitine is the carrier molecule that takes fuel in the form of acetate groups from the cell across mitochondrial membranes where it is needed to fuel energy production by Kreb’s citric acid cycle and oxidative phosphorylation. Acetate groups in the cell bind to carninine to form acetyl L-carnitine, which can then pass through the mitchondrial membrane. The acetate groups is then given up and L-carnitine passes back through the mitochondrial membrane into the cell in order to pick up another molecule of acetate. Using the car analogy, carnitine is like the nozzle on the fuel pump that delivers fuel into the tank of your tank of your car where it is needed.

Carnitine can be made in both the liver and the kidney from cysteine and methionine (both amino acids in animal protein) and requires iron and vitamin C for its synthesis. In muscle meats L-carnitine makes up 0.1% of dry matter. There is very little carnitine in plant derived foods, which may partly explain why vegetarianism seems to be a risk factor for chronic fatigue.

A typical sort of dose to treat problems associated with poor mitochondrial function is 2 grams a day. Studies have shown it is highly effective in ischaemic heart disease. It has also been trialled in the treatment of chronic fatigue syndrome…” Dr. Sarah Myhill

Related Link Here

I take 2 grams a day WITH r-lipoic acid (this is what the body creates FROM alpha lipoic acid) in order to optimize their benefit. Ratio of 1:1. It’s an energy revolution when I’m careful not to overdo the activity. I consider these 2 supplements a daily must.

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